Health

New Drugs Could Help Humans Live to be 150

| by Michael Allen
article imagearticle image

New drugs that could help people to live to be 150 years old may be available within five years, reports the Daily Mail.

The new drugs are synthetic versions of resveratrol, which is normally found in red wine. 

Resveratrol is believed to have an anti-aging effect because it switches on a protein called SIRT1.

SIRT1 is switched on naturally by calorie restriction and exercise, but it can also be enhanced through activators.

The most common activator is resveratrol, but stronger synthetic activators are being developed.

GlaxoSmithKline has been testing the medications on patients suffering with medical conditions such as cancer, diabetes and heart disease.

Writing in the journal Science, Harvard University Genetics Professor David Sinclair stated: "Our drugs can mimic the benefits of diet and exercise, but there is no impact on weight. Ultimately, these drugs would treat one disease, but unlike drugs of today, they would prevent 20 others. In effect, they would slow aging. In the history of pharmaceuticals, there has never been a drug that tweaks an enzyme to make it run faster."

There have already been promising results in some trials with implications for cancer, cardiovascular disease and cardiac failure, type 2 diabetes, Alzheimer's and Parkinson's diseases, fatty liver disease, cataracts, osteoporosis, muscle wasting, sleep disorders and inflammatory diseases such as psoriasis, arthritis and colitis.

Limited trials have been carried out in people with type 2 diabetes and the skin inflammatory disease, psoriasis.

Source: Daily Mail